发表论文：

1. Zhao S^#, Miao C^#, Gao X^#, Li Z^#, Eriksson JE*, Jiu Y*. Vimentin cage - A double-edged sword in host anti-infection defense. Curr Opin Cell Biol. 2024 Jan 2;86:102317.

2. Zhao S^#, Xu QP^#, Cui YQ^#, et al., Jiu Y. Salmonella hijacks cytoskeletal vimentin via SopB-Cdc42-MEK1/2 to maintain replication vacuoles for efficient infection. Nat Commun. 2023 Jan 30;14(1):478.

3. Miao CL^#, Zhao S^#, et al., Jiu Y. The diverse actions of cytoskeletal vimentin in bacterial infection and host defense. J Cell Sci. 2023 Jan 1;136(1):jcs260509.

4. Ouyang Z^#, Zhao S^#, Yao S^#, et al., Jiu Y. Multifaceted function of myosin-18, an unconventional class of the myosin superfamily. Front Cell Dev Biol. 2021 Feb 9;9:632445.

5. Zhao S^#, Shi X^#, Zhang Y^#, et al, Jiu Y. Myosin-18B promotes mechanosensitive CaMKK2-AMPK-VASP regulation of contractile actin stress fibers. iScience. 2020;23(4):100975.

6. Zhao S^#, Cai J^#, et al., Jiu Y. Different formins restrict localization of distinct tropomyosins on dorsal stress fibers in osteosarcoma cells. Cytoskeleton. 2020;77(1-2):16-24.

7. Zhang N^#, Zhao SS^#, et al., He HW. A novel biphenyl compound IMB-S7 ameliorates hepatic fibrosis in BDL rats by suppressing Sp1-mediated integrin αv expression. Acta Pharmacol Sin. 2020;41(5):661-669.

8. Zhao SS^#, Li NR^#, et al., He HW, Shao RG. D-chiro-inositol effectively attenuates cholestasis in bile duct ligated rats by improving bile acid secretion and attenuating oxidative stress. Acta Pharmacol Sin. 2018 Feb;39(2):213-221.

9. Zhao S, et al., He H, Shao RG. Protective effect of gastrodin on bile duct ligation-induced hepatic fibrosis in rats. Food Chem Toxicol. 2015 Dec; 86: 202-7. (IF: 3.584)

专利：

1. 酒亚明，赵双双，张悦。MAPK通路抑制剂在抗病毒感染中得应用。中国专利申请号：202211542706.1。

2. 酒亚明，赵双双。MAPK通路抑制剂在抗病原体感染中得应用。中国专利申请号：202111414365.5。

3. Hongwei Tian; Xingang Wang; Rongguang Shao; Yucheng Wang; Naren Li; Shi-Ying Cai; Hongwei He; Juxian Wang; Shuangshuang Zhao; Maoxu Ge; Jinfeng Ren; Use of (Benzenesulfonamido) Benzamide compounds for inhibiting liver fibrosis。美国专利号：US10933038B2。

4. 邵荣光，赵双双，李娜仁，于滨，何红伟，马艳，葛茂旭。天麻素和天麻粉在制备抗肝纤维化药物中的应用。专利号：ZL 201510019139.5。

5. 邵荣光，李娜仁，赵双双，金中甲，何红伟，赵龙吟，赵午莉，刘虹，葛茂旭，张镱萱。D-手性肌醇在制备抗肝纤维化药物中的应用。专利号：ZL 201610112806.9。

6. 邵荣光，王玉成，李娜仁，蔡仕英，何红伟，王菊仙，赵双双，葛茂旭，任金凤。2-苯磺酰胺基苯甲酰胺类化合物在肝损伤保护和肝纤维化防治中的应用。专利号：ZL 201510830392.9。

近期，我们利用多种显微成像、组学分析和高通量药物筛选等技术，首次阐述了沙门氏菌利用宿主细胞的中间丝vimentin保护其用于增殖的复制泡，进而促进细菌感染的功能和分子机理。与此同时，筛选并鉴定出了一个临床小分子药物可通过调控vimentin的动态重构抑制沙门氏菌感染（Nature Communications, 2023）。主持国家自然基金青年项目一项，入选中国科学院青年创新促进会。

本实验室结合细胞生物学、病原学、药效学以及多种先进的生物成像手段，以细胞骨架中间丝为主要研究对象，探究病原体感染与宿主细胞互作的病理基础与规律，致力于为相关疾病的精准治疗提供新的药物靶点和治疗策略。