病毒免疫逃逸与疫苗开发研究组招聘启事

[研究组简介] Introduction

中国科学院上海免疫与感染研究所现代疫苗中心专注于重大传染性疾病的人用疫苗、肿瘤疫苗和动物疫苗开发，通过病毒学、免疫学和疫苗学的基础研究，指导新型疫苗的设计与应用。

Geoffrey Smith院士（英国皇家科学院、德国科学院），国际著名痘病毒研究专家，于2025年2月正式加入中国科学院上海免疫与感染研究所，成为现代疫苗中心首席科学家、病毒免疫逃逸与疫苗开发研究组组长。Smith院士是国际痘病毒研究权威，对痘病毒家族的生物学机制和疫苗开发进行了深入研究。他率先利用痘苗病毒开发针对流感、疟疾和乙肝等传染病的新型疫苗，同时以痘苗病毒为模式病毒，全面解析了痘病毒的免疫逃逸机制、宿主相互作用及病毒复制策略。

Smith院士的研究成果发表在Nature、Science和Cell等国际顶尖学术期刊，并被广泛引用。他曾发现多个痘病毒免疫逃逸和复制的新机制，为病毒学、免疫学和疫苗学研究提供了重要启示。此外，Smith院士还是病毒学权威教材《费氏病毒学》（Fields of Virology）的撰稿人之一，也是该领域的重要学术奠基人之一。Smith院士团队将聚焦痘病毒免疫逃逸及新型疫苗开发领域的研究，同时，将与陆泳旭研究员的团队进行深度合作，开展开创性科学研究。

实验室经费充足，科研氛围浓厚，诚邀优秀毕业生与青年学者加入！

The Vaccine Research Centre at the Shanghai Institute of Immunity and Infection, Chinese Academy of Sciences, focuses on the development of vaccines for infectious diseases and cancers of humans, and for major infectious diseases of animals. Through fundamental research in virology, immunology, and vaccinology, the centre guides the design and application of novel vaccines.

Professor Geoffrey Smith (Fellow of the Royal Society, UK, and the German Academy of Sciences), serves as the Chief Scientist of the Vaccine Research Centre and the head of the Viral Immune Evasion and Vaccine Development Research Group. As a postdoc, he established the principle of using genetically engineered viruses as new vaccines against a broad range of infectious diseases. Using vaccinia virus as a model, Professor Geoffrey Smith’s lab has conducted in-depth studies on the biological mechanisms of poxvirus replication, host interactions and immune evasion. This information is being applied to develop vacciens of greater safety and potency.

Professor Smith's research findings have been published in international academic journals such as Nature, Science, and Cell, and have been widely cited. He has discovered several new mechanisms of poxvirus immune evasion and replication, providing significant insights for virology, immunology, and vaccinology. Additionally, Professor Smith is one of the contributors to the authoritative virology textbook Fields, Virology and is a key academic founder in the field. Professor Smith leads a research group within the Vaccine Research Centre, Shanghai Institute of Immunity and Infection, Chinese Academy of Sciences, that is focused on poxvirus immune evasion and the development of vaccines. His research group will collaborate closely with the team of Dr Lu Yongxu to conduct groundbreaking scientific research.

The laboratory is well-funded with a strong research atmosphere, and we warmly welcome outstanding graduates and young scholars to join us!

[招聘岗位] Job Openings

博士后（编号：GS-P-01）：2人

工作内容：

1. 开展以下领域的科研课题：

（1）筛选新的抗病毒宿主蛋白；

（2）鉴定新的抗病毒机制；

（3）鉴定新的病毒免疫逃逸策略；

（4）构建重组痘病毒载体疫苗。

2. 参与课题组科研项目的合作与研究生指导；

3. 协助课题组科研项目的申请与实施。

应聘条件：

1. 年龄不超出35周岁，即将获得或近三年内已获得病毒学、细胞生物学、免疫学或基础医学等相关领域博士学位，并在SCI期刊发表过或即将发表第一作者论文；

2. 科学态度严谨，具备独立科研能力和团队合作精神；

3. 具备分子和细胞生物学实验经验；

4. 具备小型动物攻毒实验经验者优先。

Postdoctoral Researchers (Job Number: GS-P-01): 2 positions

Job Responsibilities:

1.Conduct research projects in the following areas:

(1) Screening for new antiviral host proteins;

(2) Identifying new antiviral mechanisms;

(3) Identifying new viral immune evasion strategies;

(4) Constructing recombinant poxvirus vector vaccines.

2.Participate in collaborative research projects within the group and guide postgraduate students;

3.Assist in the application and implementation of research projects within the group.

Qualifications:

1.Age not exceeding 35 years, about to receive or having received a PhD in virology, cell biology, immunology, or basic medicine within the last three years, with first-author papers published or about to be published in SCI journals;

2.A rigorous scientific attitude, independent research capabilities, and a team spirit;

3.Experience in molecular and cellular biology experiments;

4.Experience in small animal challenge experiments is welcome but not essential.

[薪酬待遇与职业发展] Compensation and Career Development

1. 研究所提供补充住房公积金、保健津贴、工作餐补贴、交通补贴、职工补充互助医疗保障计划、健康体检等配套福利保障，符合条件的员工还可申请市级或区级租房补贴、纳入事业编制、获得货币化住房补贴、申请上海市户籍等。

2. 研究所支持博士后申报国家“博士后创新人才支持计划”、中国科学院“特别研究助理资助项目”“中国博士后科学基金”、上海市“超级博士后”及各类科技项目和青年人才项目等 10 余项。博士后全部纳入“中国科学院特别研究助理岗位”，博士后进站即落户上海，在站期间可参与所内副研究员岗位竞聘。

The institute provides supplementary housing provident fund, health allowances, meal subsidies, transportation subsidies, employee supplementary mutual medical insurance, health check-ups, and other benefits. Eligible employees can also apply for municipal or district-level housing subsidies, inclusion in the establishment, monetary housing subsidies, and Shanghai household registration.

The institute supports postdoctoral researchers in applying for national "Postdoctoral Innovative Talent Support Programme," Chinese Academy of Sciences "Special Research Assistant Funding Programme," "China Postdoctoral Science Foundation," Shanghai "Super Postdoctoral" programme, and various scientific and youth talent programmes, totalling more than 10. All postdoctoral researchers are included in the "Chinese Academy of Sciences Special Research Assistant Position," and postdocs will be registered in Shanghai upon entry. During their tenure, they can participate in the competition for associate researcher positions within the institute.

[应聘方式] Application Method

请将以下应聘材料通过电子邮件同时发至hrips@siii.cas.cn和luyongxu@siii.cas.cn邮箱，邮件标题请注明“应聘Geoffrey研究组**岗位（岗位编号***）”。初审合格后，将统一通知面试，择优录用。

1. 中、英文个人简历

2. 自荐信

3. 学历学位证书、身份证扫描件

4. 2封导师推荐信（应聘博士后需提供，其中一封为博士期间导师的推荐信）

Please send the following application materials via email to both hrips@siii.cas.cn and luyongxu@siii.cas.cn, with the email subject titled "Application for Geoffrey Research Group ** Position (Job Number ***)". After initial review, interviews will be arranged uniformly, and the best candidates will be selected.

Chinese and English personal CVs;

Cover letter;

Scanned copies of academic degree certificates and ID card;

Two recommendation letters (required for postdoctoral applicants, one of which should be from the PhD supervisor).